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Other nicely researched nAChR genes involve the CHRNA4 and CHRNB2, that have been associated as Autosomal Dominant Nocturnal Frontal Lobe Epilepsy (ADNFLE) genes.[42][46] Each of those nAChR subunits are existing in the brain as well as the occurrence of mutations in both of these subunits trigger a generalized variety of epilepsy. Examples contain

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